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Marsupials and eutherian mammals typically have an even number of nipples arranged bilaterally, from as few as two to as many as 19.

75% of the lymph is drained through the axillary lymph nodes located near the armpit.

A poor latch results in insufficient nipple stimulation to create the let down reflex.

The nipple is poorly stimulated when the baby latches on too close to the tip of the nipple.

The skin of the nipple is rich in a supply of special nerves that are sensitive to certain stimuli: these are slowly-adapting and rapidly-adapting cutaneous mechanoreceptors.

Mechanoreceptors are identified respectively by Type I slowly-adapting with multiple Merkel corpuscle end-organs and Type II slowly-adapting with single Ruffini corpuscle end-organs, as well as Type I rapidly-adapting with multiple Meissner corpuscle end-organs and Type II rapidly-adapting with single Pacinian corpuscle end-organs.

The nipple is surrounded by the areola which is often a darker color than the surrounding skin.

When the baby suckles or stimulates the nipple, oxytocin levels rise and small muscles in the breast contract and move the milk through the milk ducts.

The result of nipple stimulation by the newborn helps to move breast milk out through the ducts and to the nipple.

It is often called a teat when referring to non-humans.

Teat can also be used to describe the flexible mouthpiece of a baby bottle.

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In humans, nipples of both males and females can be stimulated as part of sexual arousal.

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